Publications | aslam'schemistry

Patents from IIT Ropar

A. C. Shaikh and P. Singh. A METHOD OF SYNTHESIS OF ORGANIC FLUOROPHORE, Patent filing date: 2025-08-05. Patent Application No. 202511075893

INDEPENDENT CAREER AT IIT ROPAR:

37. Palladium-Catalyzed Carbo-Oxygenative Cyclization of Chloroprenes

to Access Organo-fluorophores.

Puja Singh, Sanjay S. Bisht, Manoj Mane, J. A. Malik, Manwi Shankar,

Boddu S. Naidu, Javed N. Agrewala, and A. C. Shaikh*,

Chemrxiv, preprint 2025. DOI: 10.26434/chemrxiv-2025-9v43h

36. [7]Helicene-Backboned Quaternary Ammonium Salts: Synthesis,

Photophysical Investigation and Lysosomal Tracking.

Deepshikha, Sanjay S. Bisht, Nand Lal, Puja Singh, J. A. Malik,

Javed N. Agrewala, and A. C. Shaikh*,

Journal of Materials Chemistry B, 2025, accepted!

https://doi.org/10.1039/D5TB01192B

35. Unveiling Palladium-catalysis to Access Oxepino-indole Through

Sequential Oxycyclization Utilizing η³-π-allyl Reactivity.

Puja Singh, Manoj V. Mane, Sudeo K. Mahto and A. C. Shaikh*,

Organic Letters, 2025, 27, 30, 8217–8222!

https://pubs.acs.org/doi/10.1021/acs.orglett.5c02333

34. Ruthenium-Catalyzed Intramolecular Allene–alkyne Cascade

Cyclization: Access to the Sulfone-cyclopenta[a]naphthalene Core.

Puja Singh, Deepshikha, Nand Lal, Manoj V. Mane* and A. C. Shaikh*

Organic Letters, 2025, 27, 1153–1158

https://pubs.acs.org/doi/10.1021/acs.orglett.4c04659

33. Red-Light Mediated Formylation of Indoles Using Helical Carbenium

Ion as Photoredox Catalyst.

Nand Lal, Deepshikha, Puja Singh and A. C. Shaikh*,

Chem. Commun., 2025, 61, 3005-3008

https://pubs.rsc.org/en/content/articlelanding/2025/cc/d4cc06225f

32. Isolated Neutral Organic Radical Unveiled Solvent-Radical Interaction

In Highly Reducing Photocatalysis.

A. C. Shaikh, Md M. Hossain, J. Moutet, A. Kumar, R. Kaur,

B. Thompson, V. Huxter, and T. L. Gianetti,

Angew. Chem. Int. Ed., 2025, 64, e202420483

https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202420483

31. Electro-photochemical Functionalization of C(sp3)–H bonds: Synthesis

toward Sustainability.

Puja Singh, Burkhard Koenig*, and Aslam C. Shaikh*,

JACS Au 2024, 4, 3340–3357 (Perspective)

https://doi.org/10.1021/jacsau.4c00496

30. Red Light–Blue Light Chromoselective C(sp2)–X

Bond Activation by Organic Helicenium- Based Photocatalysis

Md Mubarak Hossain, Aslam C. Shaikh, Ramandeep Kaur, and

Thomas L. Gianetti

J. Am. Chem. Soc. 2024, 146, 12, 7922–7930. (IIT Ropar affiliation)

https://doi.org/10.1021/jacs.3c13380.

29. Allylsilane as a versatile handle in photoredox catalysis.

Nand Lal, S. B. Shirsath, P. Singh, Deepshikha, and A. C. Shaikh,*

Chem. Commun., 2024, 60, 4633-4647.

https://doi.org/10.1039/D4CC00734D

28. Solvated Electrons: Dynamic Reductant in Visible Light Photoredox

Catalysis.

P. Singh, Nand Lal, and A. C. Shaikh,*

Adv. Synth. Catal. 2024, 366, 1906 – 1921.

https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsc.202400001

27. Photochemical Sonogashira Coupling Reactions: Beyond Traditional

Palladium-Copper Catalysis.

P. Singh and A. C. Shaikh,*

Chem. Commun. 2023, 59, 11615-11630. DOI: 10.1039/D3CC03855F.

Publications and Patents before Joining IIT Ropar

26. M. Barsukova, A. Sapianik, V. Guillerm, A. Shkurenko, A. C. Shaikh, P. Parvatkar, P. Bhatt, M. Bonneau, A. Alhaji, O. Shekhah, S. R.G. Balestra, R. Semino, G. Maurin and M. Eddaoudi, "Face-directed assembly of tailored isoreticular MOFs using centering structure-directing agents, Nature Synthesis, 2023, doi.org/10.1038/s44160-023-00401-8.

25. A. El-Zohry, T. Solling, A. Hussien, O. Shekhah, A. C. Shaikh, and M. Eddaoudi, A The Charge Transfer Process of Solvated Hydrogen-Bonded Organic Network, The Journal of Physical Chemistry, 2023, 127, 9050–9057

24. P. T. Parvatkar, S. Kandambeth, A. C. Shaikh, I. Nadinov, J. Yin, V. S. Kale, G. Healing, A.-H. Emwas, O. Shekhah, O. F. Mohammed and M. Eddaoudi, A Tailored COF for Visible-light Photosynthesis of 2,3-Dihydrobenzofurans, J.Am. Chem.Soc. 2023, 145, 5074–5082. doi.org/10.1021/jacs.2c10471.

22. Md M. Hossain*, A. C. Shaikh*, J. Moutet, and T. L. Gianetti; Photocatalytic α-Arylation of cyclic ketones; Nature Synthesis, 2022, 1, 147-157. DOI: 10.1038/s44160-021-00021-0; (*work equally contributed); ChemRxiv.: doi.org/10.33774/chemrxiv-2021-gsq6s.

21. A. C. Shaikh, J. M. Veleta, J. Moutet and T. L. Gianetti, Trioxatriangulenium (TOTA+) as a Robust Carbon-based Lewis Acid in Frustrated Lewis Pair Chemistry; Chem. Sci., 2021 12, 4841-4849 (Impact factor-9.969); ChemRxiv.: DOI-10.26434/chemrxiv.13071821. doi.org/10.1039/D0SC05893A.

20. A. C. Shaikh, J. Moutet, J. M. Veleta, Md M.Hossain, J. Bloch, A. V. Astashkin and T. L. Gianetti, Persistent, Highly Localized, and Tunable [4]Helicene Radicals; Chem. Sci., 2020, 11, 11060-11067 (Impact factor-9.969); ChemRxiv. doi.org/10.26434/ chemrxiv.12408245.v2. doi.org/10.1039/D0SC04850J.

19. A. C. Shaikh, J. M. Veleta, J. Bloch, H. J. Goodman, T. L. Gianetti, Syntheses of Phosphonium salt from Phosphines and carbenium: Efficient CO2 Fixation and Phase-Transfer Catalysts; Eur. J. Org. Chem., 2020, 17, 2553 - 2559. (Impact factor-3.261) doi.org/10.1002/ejoc.202000221.

18. A. J. Smaligo, J. Wu, N. R. Burton, A. S. Hacker, A. C. Shaikh, J. C. Quintana, R. Wang, C. Xie, and O. Kwon, Oxodealkenylative cleavage of alkene C(sp3)–C(sp2) bonds: A practical method for introducing carbonyls in chiral pool materials; Angew. Chem. Int. Ed. 2020, 59, 1211 –1215. (Impact factor-16.82). doi.org/10.1002/anie.201913201.

17. A. C. Shaikh and Ohyun Kwon, Phosphine-Catalyzed [3 + 2] Annulation: Synthesis of Ethyl 5-(tert-Butyl)-2-Phenyl-1-Tosyl-3-Pyrroline-3-Carboxylate; Org. Synth. 2019, 96, 214-231. (Impact factor-0.48) doi.org/10.15227/orgsyn.096.021.

16. A. C. Shaikh and Ohyun Kwon, Phosphine-Catalyzed [4+2] Annulation: Synthesis of Ethyl 6-Phenyl-1-Tosyl-1,2,5,6-Tetrahydropyridine-3-Carboxylate; Org. Synth. 2019, 96, 110-123. (Impact factor-0.48) doi.org/10.15227/orgsyn.096.0110.

WORK AT DOCTORAL STUDIES:

15. A. C. Shaikh, S. Banerjee, R. D. Mule, Saibal Bera and N. T. Patil, External Oxidant-Dependent Reactivity Switch in Copper-Mediated Intramolecular Carboamination of Alkynes: Access to New Classes of Fluorescent Ionic Nitrogen-Doped Polycyclic Aromatic Hydrocarbons; J. Org. Chem., 2019, 84, 4120–4130. (Impact factor-4.354) doi.org/10.1021/acs.joc.9b00120.

14. A. C. Shaikh, M. E. Varma, R. D. Mule, S. Banerjee, P. P. Kulkarni, and N. T. Patil, Ionic Pyridinium-Oxazole Dyads: Design, Synthesis, and their Application in Mitochondrial Imaging; J. Org. Chem., 2019, 84, 1766–1777. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b02528.

13. A. C. Shaikh, D. S. Ranade, P. R. Rajamohanan, P. P. Kulkarni, and N. T. Patil, Oxidative Intramolecular 1,2-Amino-oxygenation of Alkynes under Au(I)/Au(III)-Catalysis: Discovery of Pyridinium-Oxazole Dyad as Novel Ionic Fluorophore; Angew. Chem. Int. Ed., 2017, 56, 757-761. (Impact factor-16.82) doi.org/10.1002/anie.201609335.

12. A. C. Shaikh, D. R. Shinde, and N. T. Patil, Gold vs Rhodium Catalysis: Tuning Reactivity through Catalyst Control in the C-H Alkynylation of Isoquinolones; Org. Lett., 2016, 18, 1056-1059. (Highlihted in ChemInform Abstract) (Impact factor-6.005) doi.org/10.1021/acs.orglett.6b00175.

11. A. C. Shaikh, D. S. Ranade, S. Thorat, A. Maity, P. P. Kulkarni, R. G. Gonnade, P. Munshi, and N. T. Patil, Highly Emissive Organic Solids with Remarkably Broad Color Tunability Based on N, C Chelate Four-Coordinate Organoborons; Chem. Commun., 2015, 51, 16115-16118. (Impact factor-6.222) doi.org/10.1039/C5CC06351E.

10. A. C. Shaikh, S. Shalini, R. Vaidhyanathan, M. V. Mane, A. K. Barui, C. R. Patra, Y. Venkatesh, P. R. Bangal, and N. T. Patil, Identifying Solid Luminogens through Gold-catalyzed Intramolecular Hydroarylation of Alkynes; Eur. J. Org. Chem., 2015, 4860-4867. (Impact factor-3.261) doi.org/10.1002/ejoc.201500503.

9. D. More, G. Shinde, A. C. Shaikh and M. Muthukrishnan, Oxone Promoted Dehydrogenative Povarov Cyclization of N-Aryl Glycine Derivatives: An Approach towards Quinoline Fused Lactones and Lactams; RSC Adv., 2019, 9, 30277-30291. (Impact factor-3.73) doi.org/10.1039/C9RA06212B.

8. G. S. Ghotekar, S. R. Shirsath, A. C. Shaikh and M. Muthukrishnan, Palladium-catalyzed [4+2] annulation of Sulfonyl allenols with p-Quinone Methides: Highly Regio- and Diastereoselective Access to Spiro[5.5]undeca-1,4-dien-3-one Scaffolds; Chem. Commun., 2020, 56, 5022-5025. (Impact factor-6.222) doi.org/10.1039/D0CC01005G.

7. G. S. Ghotekar, A. C. Shaikh and M. Muthukrishnan, Transition Metal Free Benzannulation of tricarbonyl Derivatives with Arynes: Facile access to 1,3-Dinaphthol Precursors for the Synthesis of Rhodamine dye Analogues; J. Org. Chem., 2019, 84, 2269–2276. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b02560.

6. R. D. Mule, A. C. Shaikh, Amol B. Gade, S. Bera, and N. T. Patil, A new class of N-doped ionic PAHs via intramolecular [4+2]-cycloaddition between arylpyridines and alkynes; Chem. Commun., 2018, 54, 11909-11912. (Highlighted in Synfacts 02-01-2019, 15(01), 0015, DOI: 10.1055/s-0037-1611930) (Impact factor-6.222) doi.org/10.1039/C8CC05743E.

5. S. R. Shirsath, G. H. Shinde, A. C. Shaikh and M. Muthukrishnan, Accessing the α-aryl Nitriles via BF3.OEt2 Mediated Cyanation of para-Quiononemethides using ter-Butyl isocyanide as a Cyanide source; J. Org. Chem., 2018, 83, 12305–12314. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b01926.

4. V. Nalla, G. S. Ghotekar, M. B. Thoke, R. Velayudham, A. C. Shaikh, M. Karthikeyan and M. Muthukrishnan, Transition Metal Free Regio-selective C-H Hydroxylation of Chromanones towards Synthesis of Hydroxyl-Chromanones using PhI(OAc)2 as an Oxidant; Chem. Commun., 2018, 54, 2252-2255. (Impact factor-6.222) doi.org/10.1039/C7CC08588E.

3. V. Nalla, A. C. Shaikh, S. Bapat, R. Vyas, M. Karthikeyan, P. Yogeeswari, D. Sriram, and M. Muthukrishnan, Identification of potent chromone embedded [1,2,3]-triazoles as novel antitubercular agents; RSC Open Science, 2018, 5, 171750. (Impact factor-2.963) doi.org/10.1098/rsos.171750.

2. P. S. Shinde, A. C. Shaikh, and N. T. Patil, Efficient Access to Alkynylated Quinalizinones via Gold(I)- catalyzed Aminoalkynylation of Alkynes; Chem. Commun., 2016, 52, 8152-8155. (Highlihted in ChemInform Abstract) (Impact factor-6.222) doi.org/10.1039/C6CC03414D.

1. A. H. Bansode, A. C. Shaikh, R. D. Kavthe, S. Thorat, R. G. Gonnade, and N. T. Patil, Catalyst Dependent Selectivity in Relay Catalytic Branching Cascade; Chem. Eur. J., 2015, 21, 2319-2323. (Selected as a Hot Article and Inside Back Cover) (Impact factor-5.020) doi.org/10.1002/chem.201405736

LIST OF PATENTS:

N. T. Patil, A. C. Shaikh, P. P. Kulkarni, D. S. Ranade; Pyridinium oxazole dyad scaffold and a process for preparation thereof; U. S. Patent-US10711012B2 (Application granted on 2020-07-14, filling date: 2017-10-17); U. S. Patent- US11021490B2 (Application granted on 2021-06-01, filing date: 2020-02-26); WIPO (PCT) WO2018073838A1 (Publication date: 2018-04-26, filling date: 2017-10-17); Indian Patent: IN 201611035581 (Filling date: 2016-10-18).
N. T. Patil, A. C. Shaikh; N C-Chealtes four-coordinate organoborones with full colour tenability; U. S. Patent-US10301330B2 (Application granted on 2019-05-28, filling date: 2016-06-22); WIPO (PCT)- WO2016207910A1 (Publication date: 2016-12-29, filling date: 2016-06-22); Indian Patent: IN 2015DE01844 (filling date: 2016-06-22)
O. Kwon, C. Xie, J. Zhao, N. J. Dupper, A. C. Shaikh, J.-N. Chen and A. Langenbacher, Compounds, compositions, and methods for modulating calcium ion homeostasis; WIPO (PCT)- WO2021163493A1 (Publication date: 2021-08-19, filling date: 2021-02-12; U. S. Patent- US202062975541P, Application number- PCT/US2021/017869 (Filing date: 2021-02-12).

ACS Research Group

Department of Chemistry, IIT Ropar

Patents from IIT Ropar

Publications and Patents before Joining IIT Ropar