Publications | aslam'schemistry

Patents from IIT Ropar

A. C. Shaikh and P. Singh. A METHOD OF SYNTHESIS OF ORGANIC FLUOROPHORE, Patent filing date: 2025-08-05. Patent Application No. 202511075893

INDEPENDENT CAREER AT IIT ROPAR:

36. Deepshikha, Sanjay S. Bisht, Nand Lal, Puja Singh, J. A. Malik,

Javed N. Agrewala, and A. C. Shaikh*, [7]Helicene-Backboned

Quaternary Ammonium Salts: Synthesis, Photophysical Investigation,

and Lysosomal Tracking. Journal of Materials Chemistry B, 2025, accepted!

https://doi.org/10.1039/D5TB01192B

35. Puja Singh, Manoj V. Mane, Sudeo K. Mahto and A. C. Shaikh*,

Unveiling Palladium-catalysis to Access Oxepino-indole Through

Sequential Oxycyclization Utilizing η³-π-allyl Reactivity.

Organic Letters, 2025, 27, 30, 8217–8222!

https://pubs.acs.org/doi/10.1021/acs.orglett.5c02333

34. Puja Singh, Deepshikha, Nand Lal, Manoj V. Mane* and A. C. Shaikh*,

Ruthenium-Catalyzed Intramolecular Allene–alkyne Cascade Cyclization:

Access to the Sulfone-cyclopenta[a]naphthalene Core.

Organic Letters, 2025, 27, 1153–1158

https://pubs.acs.org/doi/10.1021/acs.orglett.4c04659

33. Nand Lal, Deepshikha, Puja Singh and A. C. Shaikh*, Red-Light Mediated

Formylation of Indoles Using Helical Carbenium Ion as Photoredox Catalyst.

Chem. Commun., 2025, 61, 3005-3008

https://pubs.rsc.org/en/content/articlelanding/2025/cc/d4cc06225f

32. A. C. Shaikh, Md M. Hossain, J. Moutet, A. Kumar, R. Kaur,

B. Thompson, V. Huxter, and T. L. Gianetti, Isolated Neutral Organic

Radical Unveiled Solvent-Radical Interaction in Highly Reducing

Photocatalysis.

Angew. Chem. Int. Ed., 2025, 64, e202420483

https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202420483

31. Puja Singh, Burkhard Koenig*, and Aslam C. Shaikh*,

Electro-photochemical Functionalization of C(sp3)–H bonds: Synthesis

toward Sustainability.

JACS Au 2024, 4, 3340–3357 (Perspective)

https://doi.org/10.1021/jacsau.4c00496

30. Md Mubarak Hossain, Aslam C. Shaikh, Ramandeep Kaur, and

Thomas L. Gianetti,"Red Light–Blue Light Chromoselective C(sp2)–X

Bond Activation by Organic Helicenium- Based Photocatalysis",

J. Am. Chem. Soc. 2024, 146, 12, 7922–7930. (IIT Ropar affiliation)

https://doi.org/10.1021/jacs.3c13380.

29. Nand Lal, S. B. Shirsath, P. Singh, Deepshikha, and A. C. Shaikh,*

Allylsilane as a versatile handle in photoredox catalysis.

Chem. Commun., 2024, 60, 4633-4647.

https://doi.org/10.1039/D4CC00734D

28. P. Singh, Nand Lal, and A. C. Shaikh,* Solvated Electrons: Dynamic

Reductant in Visible Light Photoredox Catalysis.

Adv. Synth. Catal. 2024, 366, 1906 – 1921.

https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsc.202400001

27. P. Singh and A. C. Shaikh,* Photochemical Sonogashira Coupling

Reactions: Beyond Traditional Palladium-Copper Catalysis.

Chem. Commun. 2023, 59, 11615-11630. DOI: 10.1039/D3CC03855F.

Publications and Patents before Joining IIT Ropar

26. M. Barsukova, A. Sapianik, V. Guillerm, A. Shkurenko, A. C. Shaikh, P. Parvatkar, P. Bhatt, M. Bonneau, A. Alhaji, O. Shekhah, S. R.G. Balestra, R. Semino, G. Maurin and M. Eddaoudi, "Face-directed assembly of tailored isoreticular MOFs using centering structure-directing agents, Nature Synthesis, 2023, doi.org/10.1038/s44160-023-00401-8.

25. A. El-Zohry, T. Solling, A. Hussien, O. Shekhah, A. C. Shaikh, and M. Eddaoudi, A The Charge Transfer Process of Solvated Hydrogen-Bonded Organic Network, The Journal of Physical Chemistry, 2023, 127, 9050–9057

24. P. T. Parvatkar, S. Kandambeth, A. C. Shaikh, I. Nadinov, J. Yin, V. S. Kale, G. Healing, A.-H. Emwas, O. Shekhah, O. F. Mohammed and M. Eddaoudi, A Tailored COF for Visible-light Photosynthesis of 2,3-Dihydrobenzofurans, J.Am. Chem.Soc. 2023, 145, 5074–5082. doi.org/10.1021/jacs.2c10471.

22. Md M. Hossain*, A. C. Shaikh*, J. Moutet, and T. L. Gianetti; Photocatalytic α-Arylation of cyclic ketones; Nature Synthesis, 2022, 1, 147-157. DOI: 10.1038/s44160-021-00021-0; (*work equally contributed); ChemRxiv.: doi.org/10.33774/chemrxiv-2021-gsq6s.

21. A. C. Shaikh, J. M. Veleta, J. Moutet and T. L. Gianetti, Trioxatriangulenium (TOTA+) as a Robust Carbon-based Lewis Acid in Frustrated Lewis Pair Chemistry; Chem. Sci., 2021 12, 4841-4849 (Impact factor-9.969); ChemRxiv.: DOI-10.26434/chemrxiv.13071821. doi.org/10.1039/D0SC05893A.

20. A. C. Shaikh, J. Moutet, J. M. Veleta, Md M.Hossain, J. Bloch, A. V. Astashkin and T. L. Gianetti, Persistent, Highly Localized, and Tunable [4]Helicene Radicals; Chem. Sci., 2020, 11, 11060-11067 (Impact factor-9.969); ChemRxiv. doi.org/10.26434/ chemrxiv.12408245.v2. doi.org/10.1039/D0SC04850J.

19. A. C. Shaikh, J. M. Veleta, J. Bloch, H. J. Goodman, T. L. Gianetti, Syntheses of Phosphonium salt from Phosphines and carbenium: Efficient CO2 Fixation and Phase-Transfer Catalysts; Eur. J. Org. Chem., 2020, 17, 2553 - 2559. (Impact factor-3.261) doi.org/10.1002/ejoc.202000221.

18. A. J. Smaligo, J. Wu, N. R. Burton, A. S. Hacker, A. C. Shaikh, J. C. Quintana, R. Wang, C. Xie, and O. Kwon, Oxodealkenylative cleavage of alkene C(sp3)–C(sp2) bonds: A practical method for introducing carbonyls in chiral pool materials; Angew. Chem. Int. Ed. 2020, 59, 1211 –1215. (Impact factor-16.82). doi.org/10.1002/anie.201913201.

17. A. C. Shaikh and Ohyun Kwon, Phosphine-Catalyzed [3 + 2] Annulation: Synthesis of Ethyl 5-(tert-Butyl)-2-Phenyl-1-Tosyl-3-Pyrroline-3-Carboxylate; Org. Synth. 2019, 96, 214-231. (Impact factor-0.48) doi.org/10.15227/orgsyn.096.021.

16. A. C. Shaikh and Ohyun Kwon, Phosphine-Catalyzed [4+2] Annulation: Synthesis of Ethyl 6-Phenyl-1-Tosyl-1,2,5,6-Tetrahydropyridine-3-Carboxylate; Org. Synth. 2019, 96, 110-123. (Impact factor-0.48) doi.org/10.15227/orgsyn.096.0110.

WORK AT DOCTORAL STUDIES:

15. A. C. Shaikh, S. Banerjee, R. D. Mule, Saibal Bera and N. T. Patil, External Oxidant-Dependent Reactivity Switch in Copper-Mediated Intramolecular Carboamination of Alkynes: Access to New Classes of Fluorescent Ionic Nitrogen-Doped Polycyclic Aromatic Hydrocarbons; J. Org. Chem., 2019, 84, 4120–4130. (Impact factor-4.354) doi.org/10.1021/acs.joc.9b00120.

14. A. C. Shaikh, M. E. Varma, R. D. Mule, S. Banerjee, P. P. Kulkarni, and N. T. Patil, Ionic Pyridinium-Oxazole Dyads: Design, Synthesis, and their Application in Mitochondrial Imaging; J. Org. Chem., 2019, 84, 1766–1777. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b02528.

13. A. C. Shaikh, D. S. Ranade, P. R. Rajamohanan, P. P. Kulkarni, and N. T. Patil, Oxidative Intramolecular 1,2-Amino-oxygenation of Alkynes under Au(I)/Au(III)-Catalysis: Discovery of Pyridinium-Oxazole Dyad as Novel Ionic Fluorophore; Angew. Chem. Int. Ed., 2017, 56, 757-761. (Impact factor-16.82) doi.org/10.1002/anie.201609335.

12. A. C. Shaikh, D. R. Shinde, and N. T. Patil, Gold vs Rhodium Catalysis: Tuning Reactivity through Catalyst Control in the C-H Alkynylation of Isoquinolones; Org. Lett., 2016, 18, 1056-1059. (Highlihted in ChemInform Abstract) (Impact factor-6.005) doi.org/10.1021/acs.orglett.6b00175.

11. A. C. Shaikh, D. S. Ranade, S. Thorat, A. Maity, P. P. Kulkarni, R. G. Gonnade, P. Munshi, and N. T. Patil, Highly Emissive Organic Solids with Remarkably Broad Color Tunability Based on N, C Chelate Four-Coordinate Organoborons; Chem. Commun., 2015, 51, 16115-16118. (Impact factor-6.222) doi.org/10.1039/C5CC06351E.

10. A. C. Shaikh, S. Shalini, R. Vaidhyanathan, M. V. Mane, A. K. Barui, C. R. Patra, Y. Venkatesh, P. R. Bangal, and N. T. Patil, Identifying Solid Luminogens through Gold-catalyzed Intramolecular Hydroarylation of Alkynes; Eur. J. Org. Chem., 2015, 4860-4867. (Impact factor-3.261) doi.org/10.1002/ejoc.201500503.

9. D. More, G. Shinde, A. C. Shaikh and M. Muthukrishnan, Oxone Promoted Dehydrogenative Povarov Cyclization of N-Aryl Glycine Derivatives: An Approach towards Quinoline Fused Lactones and Lactams; RSC Adv., 2019, 9, 30277-30291. (Impact factor-3.73) doi.org/10.1039/C9RA06212B.

8. G. S. Ghotekar, S. R. Shirsath, A. C. Shaikh and M. Muthukrishnan, Palladium-catalyzed [4+2] annulation of Sulfonyl allenols with p-Quinone Methides: Highly Regio- and Diastereoselective Access to Spiro[5.5]undeca-1,4-dien-3-one Scaffolds; Chem. Commun., 2020, 56, 5022-5025. (Impact factor-6.222) doi.org/10.1039/D0CC01005G.

7. G. S. Ghotekar, A. C. Shaikh and M. Muthukrishnan, Transition Metal Free Benzannulation of tricarbonyl Derivatives with Arynes: Facile access to 1,3-Dinaphthol Precursors for the Synthesis of Rhodamine dye Analogues; J. Org. Chem., 2019, 84, 2269–2276. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b02560.

6. R. D. Mule, A. C. Shaikh, Amol B. Gade, S. Bera, and N. T. Patil, A new class of N-doped ionic PAHs via intramolecular [4+2]-cycloaddition between arylpyridines and alkynes; Chem. Commun., 2018, 54, 11909-11912. (Highlighted in Synfacts 02-01-2019, 15(01), 0015, DOI: 10.1055/s-0037-1611930) (Impact factor-6.222) doi.org/10.1039/C8CC05743E.

5. S. R. Shirsath, G. H. Shinde, A. C. Shaikh and M. Muthukrishnan, Accessing the α-aryl Nitriles via BF3.OEt2 Mediated Cyanation of para-Quiononemethides using ter-Butyl isocyanide as a Cyanide source; J. Org. Chem., 2018, 83, 12305–12314. (Impact factor-4.354) doi.org/10.1021/acs.joc.8b01926.

4. V. Nalla, G. S. Ghotekar, M. B. Thoke, R. Velayudham, A. C. Shaikh, M. Karthikeyan and M. Muthukrishnan, Transition Metal Free Regio-selective C-H Hydroxylation of Chromanones towards Synthesis of Hydroxyl-Chromanones using PhI(OAc)2 as an Oxidant; Chem. Commun., 2018, 54, 2252-2255. (Impact factor-6.222) doi.org/10.1039/C7CC08588E.

3. V. Nalla, A. C. Shaikh, S. Bapat, R. Vyas, M. Karthikeyan, P. Yogeeswari, D. Sriram, and M. Muthukrishnan, Identification of potent chromone embedded [1,2,3]-triazoles as novel antitubercular agents; RSC Open Science, 2018, 5, 171750. (Impact factor-2.963) doi.org/10.1098/rsos.171750.

2. P. S. Shinde, A. C. Shaikh, and N. T. Patil, Efficient Access to Alkynylated Quinalizinones via Gold(I)- catalyzed Aminoalkynylation of Alkynes; Chem. Commun., 2016, 52, 8152-8155. (Highlihted in ChemInform Abstract) (Impact factor-6.222) doi.org/10.1039/C6CC03414D.

1. A. H. Bansode, A. C. Shaikh, R. D. Kavthe, S. Thorat, R. G. Gonnade, and N. T. Patil, Catalyst Dependent Selectivity in Relay Catalytic Branching Cascade; Chem. Eur. J., 2015, 21, 2319-2323. (Selected as a Hot Article and Inside Back Cover) (Impact factor-5.020) doi.org/10.1002/chem.201405736

LIST OF PATENTS:

N. T. Patil, A. C. Shaikh, P. P. Kulkarni, D. S. Ranade; Pyridinium oxazole dyad scaffold and a process for preparation thereof; U. S. Patent-US10711012B2 (Application granted on 2020-07-14, filling date: 2017-10-17); U. S. Patent- US11021490B2 (Application granted on 2021-06-01, filing date: 2020-02-26); WIPO (PCT) WO2018073838A1 (Publication date: 2018-04-26, filling date: 2017-10-17); Indian Patent: IN 201611035581 (Filling date: 2016-10-18).
N. T. Patil, A. C. Shaikh; N C-Chealtes four-coordinate organoborones with full colour tenability; U. S. Patent-US10301330B2 (Application granted on 2019-05-28, filling date: 2016-06-22); WIPO (PCT)- WO2016207910A1 (Publication date: 2016-12-29, filling date: 2016-06-22); Indian Patent: IN 2015DE01844 (filling date: 2016-06-22)
O. Kwon, C. Xie, J. Zhao, N. J. Dupper, A. C. Shaikh, J.-N. Chen and A. Langenbacher, Compounds, compositions, and methods for modulating calcium ion homeostasis; WIPO (PCT)- WO2021163493A1 (Publication date: 2021-08-19, filling date: 2021-02-12; U. S. Patent- US202062975541P, Application number- PCT/US2021/017869 (Filing date: 2021-02-12).

ACS Research Group

Department of Chemistry, IIT Ropar

Patents from IIT Ropar

Publications and Patents before Joining IIT Ropar